Sjögren's syndrome is a chronic autoimmune disease which can cause debilitating fatigue and pain. Diagnosis is often challenging due to the variability of symptoms and severity, and a multidisciplinary approach to management and treatment is required, yet there are few comprehensive resources covering everything clinicians need to know.
The Oxford Textbook of Sjögren's Syndrome bridges this gap by offering extensive coverage of system by system manifestations and treatments, as well as practical, evidence-based advice on diagnosing and managing this condition. Bringing together recent advances in research and therapies, this up-to-date guide covers everything clinicians need to know from the fundamental science and clinical characteristics of this condition, to the immunological and biochemical aspects, investigative procedures such as biopsy techniques and imaging modalities, and pharmacological and non-pharmacological interventions.
Contents
Section 1: Introduction
1.1:Introduction, Elizabeth J. Price and Anwar R. Tappuni
1.2:Historical background, classification and diagnostic criteria, Caroline Shiboski and Troy E. Daniels
1.3:Epidemiology and genetics of Sjögren s Syndrome, Simon Bowman
Section 2: Basic science
2.1:Biomarkers in primary Sjögren sSyndrome, Onorina Berardicurti, Charlotte G. Smith, Roberto Giacomelli, Elizabeth J. Price, and Francesca Barone
2.2:Autoantibodies and autoantigens in Sjögren s Syndrome, Aurélie Ambrosi, Albin Björk, and Marie Wahren-Herlenius
2.3:Stromal cells in Sjögren s Syndrome, Saba Nayar, Serena Colafrancesco, and Francesca Barone
Section 3: Diagnostic investigations
3.1:Clinical assessment of salivary glands function, Anwar R. Tappuni
3.2:Biopsy gland biopsy procedure and histopathology, Benjamin Fisher
3.3:Imaging in Sjögren s Syndrome, Ashok Adams
Section 4: Head and neck manifestations and clinical management
4.1:Salivary glands manifestations and management, Emily Carter
4.2:Oral manifestations and management, Anwar R. Tappuni
4.3:Dental related disease, Jennifer Fuller and Shakeel Shahdad
Section 5: Ocular manifestations and management
5.1:Ocular Manifestations of Sjögren s Syndrome, Nicola Roper, Pasquale Aragona, Maurizio Rolando, and Francisco C Figueiredo
5.2:A therapeutic strategy for Sjögren s Syndrome dry eye, Nicola Roper, Pasquale Aragona, Maurizio Rolando, and Francisco C Figueiredo
Section 6: Systemic manifestations
6.1:Cutaneous involvement and management of Sjögren s Syndrome, Thomas J Tull, Emma Benton, and David D Cruz
6.2:Musculoskeletal disease - presentation and management, Elizabeth J. Price
6.3:Renal involvement in Primary Sjögren's Syndrome, Rhys Evans and Stephen Walsh
6.4:Gastrointestinal Disease in Sjögren s syndrome, Elizabeth J. Price
6.5:Neurological complications of Sjögren s Syndrome, Aravind Ganesh, Shane Lyons, and Gabriel Yiin
6.6:Cardiovascular and Lung Manifestations of Sjögren s Syndrome, Sara Carty
6.7:Haematological Manifestations of Sjögren s Syndrome, Coziana Ciurtin and Su-Ann Yeoh
6.8:Fatigue in Sjögren s Syndrome, Coziana Ciurtin and Su-Ann Yeoh
6.9:Non-pharmacological interventions for the management of Fatigue and Constitutional Symptoms in Sjögren s Syndrome, Katie Hackett and Helen Cartner
6.1:Gynaecologic and obstetric aspects in Sjögren s Syndrome, Roberta Priori, Antonina Minniti, and Serena Colafrancesco
6.11:Sjögren s Syndrome Associated Lymphoma, Saad Rassam
Section 7: Juvenile and young adult
7.1:Juvenile and young adult onset Sjögren s Syndrome, William D. Renton, Elizabeth J. Price, and A.V. Ramanan
Section 8: Sjogren s mimics and overlaps
8.1:Mimics of Sjögren s Syndrome, Nurhan Sutcliffe
8.2:Sjögren s Syndrome overlaps, Nurhan Sutcliffe and Arabella Waller
Section 9: Experimental treatments, emerging therapies and the future
9.1:Experimental therapies in primary Sjögren s Syndrome, Benjamin Fisher
9.2:Sjögren s Syndrome Summary of Clinical Management, Elizabeth J. Price and Alan Baer
