Immunohistochemistry in Diagnostic Dermatopathology

Rapid and cost-effective immunohistochemistry plays a crucial role in diagnostic pathology, however there are currently very few textbooks dedicated to its role, especially in diagnostic dermatopathology. This comprehensive volume provides a practical guide to the application of immunohistochemistry in dermatopathology and bridges the knowledge gap by updating readers with helpful diagnostic immunostains as well as recently available ones. Organized by lines of differentiation, each chapter includes a synopsis of applicable antibodies, pertinent immunohistochemical panels, summary tables outlining the staining patterns of the entities in the differential diagnosis and case studies. The 12 chapters cover entities based on lineage including epithelial, melanocytic, lymphoid, adnexal and soft tissue. The role of immunohistochemistry as a screening test for underlying genetic syndromes, immunobullous diseases, detection of infectious agents and therapeutic purpose is also discussed in detail. This is an essential text for pathologists, dermatopathologists and residents in pathology and dermatology.

    Case studies in each chapter to aid trainees with practical understanding of the application of immunostains
    A synopsis of applicable antibodies is outlined for each chapter making for quick referencing
    Chapters are organized based on lines of differentiation, making it easy to identify entities

Table of Contents

1. Introduction to immunohistochemistry Nicholas Lawrence and Mai P. Hoang
2. Epithelial or squamous neoplasms María Teresa Fernández and Mai P. Hoang
3. Neoplasms of cutaneous appendages Mai P. Hoang
4. Inflammatory dermatoses mimicking lymphomas Mai P. Hoang and M. Angelica Selim
5. Cutaneous lymphoid neoplasms Mai P. Hoang and M. Angelica Selim
6. Melanocytic neoplasms Mai P. Hoang
7. Soft tissue neoplasms Joanna Pardal and Mai P. Hoang
8. Miscellaneous tumors Mai P. Hoang
9. Detection of genetic syndromes Mai P. Hoang
10. Immunobullous disorders Mai P. Hoang
11. Cutaneous infections Wun Ju Shieh and Mai P. Hoang
12. Therapeutic and prognostic applications Sofia Canete-Portillo and Mai P. Hoang

Mai P. Hoang is a dermatopathologist, Associate Professor of Pathology at Harvard Medical School, and currently the medical director of the Immunohistochemistry Laboratory of the Department of Pathology at Massachusetts General Hospital.

Contributors: Nicholas Lawrence, Mai P. Hoang, María Teresa Fernández, M. Angelica Selim, Joanna Pardal, Wun Ju Shieh, Sofia Canete-Portillo