Nutritional and Metabolic Bases of Cardiovascular Disease

Extraordinary advances in the understanding of the relationships between nutrition, metabolism, and cardiovascular disease have prompted a systematic reappraisal of recent knowledge in the field. Focusing on knowledge from the last two to three years, this timely volume examines and updates the role of obesity, hyperlipidemia diabetes, hypertension, thrombosis, and ageing in atherogenesis. It describes in detail the scientific and clinical evidence of the etiopathogenesis of ischemic heart disease as well as of peripheral and cerebrovascular disease. Mario Mancini (Editor), Jose Ordovas (Editor), Gabrielle Riccardi (Editor), Paolo Rubba (Editor), Pasquale Strazzullo (Editor) CONTENTS Chapter 1 Body composition and risk of metabolic diseases: lean body mass, adipose tissue, body water and electrolytes, energy intake and expenditure during lifespan, thermogenesis and regulation of body composition. (Contaldo & Scalfi & Pasanisi). Chapter 2 Optimal nutrition for health and longevity. (Mancini M & FP). Chapter 3 Gene nutrient interaction(Prof. José M. Ordovas). Chapter 4 Etiopathogenesis of obesity (Dr Angelo Tremblay). Chapter 5 Comorbidities and complications of obesity. (Contaldo Mancini M Pasanisi). Chapter 6 Cardiovascular damage in obesity and metabolic syndrome. (Prof. Oreste de Divitiis). Chapter 7 Treatment of obesity: beneficial effects on comorbidities and lifespan. (Dr G.A. Bray). Chapter 8 Obesity and diabetes in adolescents. (Dr Sonia Caprio). Chappter 9 Early Atherosclerotic lesions in childhood and adolescence (Prof. Rubba). Chapter 10 Epidemiology of obesity (James ACCETTATO). Section II Metabolic syndrome and diabetes Chapter 11 Definition and diagnostic criteria of metabolic syndrome: its value in the prediction of CVD risk.(Howard Jim and Barbara ACCETTATO). Chapter 12 Cardiac and vascular effects of adipocytokines in normal and obese individuals: the concept of cardiometabolic risk. (Prof. Roberto Vettor). Chapter 13Dietary carbohydrates, overweight and metabolic syndrome. The role of glycaemic index in a healthy diet. (Angela Rivellese & co-author). Chapter 14Wholemeal cereals consumption in relation to the CV risk (Dr Mykkanen). Chapter 15 Complex dietary patterns (mediterranean diet, vegetarian/vegan dietary models): impact on carbohydrate and lipid metabolism (Prof. Jim I. Mann). Chapter 16 Habitual physical exercise and risk of cardiovascular diseases (Prof Eduardo Farinaro). Chapter 17 Physical exercise in the prevention and treatment of obesity, diabetes, and metabolic syndrome (Anthony Karelis AD, Messier L, , Rabasa-Lhoret R). Chapter 18 Functional foods for diabetes and obesity (Riccardi). Section III Hypercholesterolemia and early atherosclerosis Chapter 19 Familial dyslipidemias: from genetics to clinical picture (Prof. Paolo Rubba). Chapter 20 HDL, reverse cholesterol transport and atherosclerosis (Prof. Guido Franceschini). Chapter 21 3. Role of Polyunsaturated Ω6 and Ω3 fatty acids and vitamin intake on atherosclerosis and CVD (Visioli / Galli). Chapter 22 Alcohol intake, dyslipidemia and CVD (Trevisan). Chapter 23 Dyslipidemia in chronic renal disease (Prof. Carmine Zoccali). Chapter 24 Subclinical hypothyroidism, dyslipidemia and cardiovascular risk.(Dr Jan Kvetny). Chapter 25 7. Genetic susceptibility and metabolic bases of atherosclerosis.(Prof. Josè Ordovas). Chapter 26 The relationship between dyslipidemia and inflammation. (Dr Licia Iacoviello). Chapter 27 Atherosclerotic lesions in childood and adolescence. (se ACCETTATO). Chapter 28 EARLY ATHEROSCLEROTIC LESIONS IN CHILDHOOD AND ADOLESCENCE (Rubba). Chapter 29 Fitosterols, plasma lipids and CVD risk. (ASSMANN ACCETTATO). Chapter 30 Nitric oxide in the development of vascular diseases and regenerative angiogenesis (Ignarro& Napoli ACCETTATO). Chapter 31 Impact of treating dyslipidemia on cardiovascular events. (Dr Zeljko Reiner). Chapter 32 Lipid Clinic: from clinical practice to experimental protocols (Prof Barry Lewis). Section IV Nutrition, hypertension and cerebrovascular disease Chapter 33 From abdominal adiposity to hypertension: mechanisms and clinical implications (Dr. Albert C. Rocchini). Chapter 34 Role of adipose tissue renin-angiotensin system in obesity and obesity/ hypertension (Prof. Stefan Engeli). Chapter 35 Relationship of dietary electrolyte intake (sodium, potassium, calcium, magnesium) to BP regulation and hypertension.(Prof. Francesco P. Cappuccio). Chapter 36 Genetic susceptibility and metabolic bases of BP salt-sensitivity.(Galletti & Strazzullo). Chapter 37 Are sodium and potassium intake independent predictors of cardiovascular and cerebrovascular events? (Prof. Pasquale Strazzullo). Chapter 38 Metabolic and dietary influences on sympathetic nervous system activity.(Prof. Vito Campese). Chapter 39 Macronutrient intake, BP and cardiovascular risk. (Prof. Jeremiah Stamler). Chapter 40 Alcohol and coffee intake, BP and cerebrovascular disorders.(Dr Jiang He). Chapter 41 Fruit and vegetable consumption, hypertension and risk of stroke.(Lydia A. L. Bazzano & Domnica Fotino). Chapter 42 Complex dietary patterns and blood pressure (mediterranean diet, vegetarian/vegan dietary models, the DASH diet, etc.)(Siani & Barba). Chapter 43 Role of metabolic alterations in hypertensive renal disease. (Prof. Carmine Zoccali). Chapter 44 12. Current experience and future perspectives for wordwide reduction of dietary salt intake (Graham A. MacGregor). Section V. Hemostasis and thrombosis: from nutritional influences to cardiovascular accidents Chapter 45 Risk factors for arterial thrombosis (De Gaetano & Donati). Chapter 46 Cellular and rheological determinants of thrombosis and fibrinolysis (Dr Chiara Cerletti). Chapter 47 Gene-gene and gene-environment interaction in arterial and vein thrombosis (Di Minno & Margaglione). Chapter 48 Intervention studies on nutrition and thrombosis (Paternò & Mancini FP). Section VI. Nutrition, metabolism and the aging process Chapter 49 The role of diet on cognitive decline (Postiglione & Gallotta). Chapter 50 Neurovascular protection in old age (Chillon & Bugnicourt). Chapter 51 Interaction between diet and genes on longevity (Perls & Puca). Chapter 52 Cardiovascular risk factors and their treatment in the oldest old (KAY TEE KHAW ACCETTATO). Chapter 53 Nutrition and life span in developing countries (Prof Arun Chockalingam)