Endometriosis

Written by an internationally well–known editor team, Endometriosis: Science and Practice is a state–of–the–art guide to this surprisingly common disease. While no cause for endometriosis has been determined, information of recent developments are outlined in this text, offering insight to improve management of symptoms medically or surgically. The first of its kind, this major textbook integrates scientific and clinical understanding of this painful disease helping to provide better patient care. Table of Contents List of Contributors. Part 1 HISTORY, EPIDEMIOLOGY, ECONOMICS. 1 Introduction (Linda C. Giudice). 2 History (Ivo Brosens and Giuseppe Benagiano). 3 Endometriosis: Epidemiology and Aetiological Factors (Fabio Parazzini , Paolo Vercellini, and Claudio Pelucchi). 4 Economic Perspective on Diagnosis and Treatment of Endometriosis (Steven Simeons and T. D′Hooghe). Part 2 PATHOGENESIS. 5 Pathogenesis: Development of the Female Reproductive Tract(Jolande A. Land and Johannes L. H. Evers). 6 Theories on the Pathogenesis of Endometriosis (Annemiek Nap). 7 Understanding the Pathogenesis of Endometriosis: Gene Mapping Studies (Jodie N. Painter, Krina T. Zondervan, and Grant W. Montgomery). 8 Pathogenesis: Epigenetics (Sun Wei Guo). Part 3 DISEASE CHARACTERIZATION. 9 Disease Classification and Behavior (G. David Adamson). 10 Peritoneal, Ovarian and Rectovaginal Endometriosis Are Three Different Entities (Jacques Donnez, Jean–Christophe Lousse, and Jean Squifflet). 11 Extrapelvic (Thoracic, Other) Endometriosis (Antonio Bobbio, Diane Damotte, Anne Gompel, and Marco Alifano). Part 4 BIOLOGICAL BASIS AND PATHOPHYSIOLOGY OF ENDOMETRIOSIS 12 Biology of Eutopic and Ectopic Endometrium in Women with Endometriosis(Petra A.B. Klemmt and Anna Starzinski–Powitz). 13 Stem Cells in Endometriosis (Caroline E. Gargett, Hirotaka Masuda, and Gareth Weston). 14 Role of Steroid Hormones: Estrogen and Endometriosis (Elke Winterhager). 15 Role of Steroid Hormones: Progesterone Signaling (Shirin Khanjani, Marwa Al–Sabbagh, and Jan J. Brosens). 16 Early Origins of Endometriosis: Role of Endocrine Disrupting Chemicals (Germaine M. Buck Louis). 17 Signaling Pathways in Endometriosis (Eutopic/Ectopic) (Julie Kim and Xunqin Yin). 18 Micro RNAs and Endometriosis (M. Louise Hull and Cristin G. Print). 19 Hox Genes and Endometriosis (Jennifer L. Kulp, Hakan Cakmak, and Hugh S. Taylor). 20 Angiogenesis and Endometriosis (Patrick Groothuis). 21 Uterine Peristalsis and the Development of Endometriosis and Adenomyosis (Gerard Leyendecker and Ludwig Wildt). 22 Pelvic Mechanisms Involved in the Pathophysiology of Pain in Endometriosis (Ian S. Fraser, Natsuko Tokushige, Alison Hey–Cunningham, Marina Berbic, and Cecilia Ng). 23 Neuroendocrine Aspects of Endometriosis–related Pain (Pamela Stratton and Karen J. Berkley). 24 Pathophysiology of Infertility in Endometriosis (Ovarian Dysfunction, Endometrium, etc.) (Bruce Lessey and Steven L. Young). 25 Role of the Immune System–Inflammation (Daniela Hornung and Ursula von Wussow). Part 5 MODELS OF ENDOMETRIOSIS. 26 Models of Endometriosis: In vitro and in vivo Models (Ruth Gruemmer). 27 Rodent–Based Chimeric Models of Experimental Endometriosis (Kaylon L. Bruner–Tran, Melinda E. McConaha, and Kevin G. Osteen). 28 Models of Endometriosis: Animal Models II. Nonhuman Primates (Asgerally T. Fazleabas). Part 6 DIAGNOSIS OF ENDOMETRIOSIS. 29 Diagnosis of Endometriosis: Surgical Historical Overview (Ayman Al–Talib, and Togas Tulandi). 30 Diagnosis of Endometriosis: Imaging (Gerard A. J. Dunselman and Regina G. H. Beets–Tan). 31 Diagnosis of Endometriosis: Biomarkers (Beata E. Seeber and Kurt T. Barnhart). 32 Diagnosis of Endometriosis: Proteomics (Andrew N. Stephens, Luk J. F. Rombauts, and Lois A. Salamonsen). 33 Diagnosis of Endometriosis: Transcriptomics (Richard O. Burney and Linda C. Giudice). Part 7 MEDICAL THERPAIES FOR PAIN. 34 Medical Therapies: RCTs/Traditional Medical Therapies (Neil Johnson). 35 Medical Therapies: Progestins (Andrew Horne and Hilary Critchley). 36 Medical Therapies: Aromatase inhibitors (Serdar E. Bulun, Erkut Attar, Bilgin Gurates, You–Hong Chen, Hideki Tokunaga, Diana Monsivais, and Mary Ellen Pavone). 37 Medical Therapies: Statins (Anna Sokalska and Antoni J. Duleba). Part 8 SURGICAL THERAPIES FOR PAIN. 38 Surgical Therapies: Principles and Triage in Endometriosis (Alan Lam, Tommaso Bignardi, and Su–Yen Khong). 39 Surgical Therapies: Peritoneal Endometriosis Surgery (Michael P. Diamond and Valerie I. Shavell). 40 Pouch of Douglas and Uterovaginal Pouch Resection for Endometriosis (Maurício Simões Abrão, Sérgio Podgaec, and Luiz Flávio Cordeiro Fernandes). 41 Surgical Treatment for Pain: RCTs in Endometriosis (Jason Abbott). 42 Surgical Therapies: Rectal/ Bowel Endometriosis (Jim Tsaltas). 43 Surgical Therapies: Ureteric dissection/and Urologic Endometriosis (Anna Rosamilia and Caroline Dowling). 44 Surgical Therapies: Robotics and Endometriosis (Arathi Veeraswamy and Camran Nezhat). Part 9 INFERTILITY AND ENDOMETRIOSIS. 45 Medical Therapy of Endometriosis: Subfertility (Hans Evers). 46 Infertility Therapy: The Role of Surgery (O. Petrucco and D. L. Healy). 47 Infertility Therapy: The Role of Assisted Reproductive Technologies (Kimberly Moon, Jeris Cox , and Alan DeCherney). 48 Ovarian Endometrioma Surgery/Fertility Preservation (Luk Rombauts). Part 10 ASSOCIATED DISORDERS. 49 Endometriosis and Autoimmunity(Srinu Pathivada and Thomas D’Hooghe). 50 Endometriosis and Cancer: Epidemiology (Paola Vigan).ò)., Edgardo Somigliana, Fabio Parazzini, and Paolo Vercellini). 51 Molecular Mechanisms Underlying Endometriosis and Endometriosis Related Cancers (Daniela Dinulescu). 52 Pregnancy and Obstetrical Outcomes in Women with Endometriosis (Henrik Falconer). 53 Sexuality (Brigitte Leeners). 54 Psychosomatic Aspects (Brigitte Leeners). 55 Endometriosis in the Adolescent Patient (Claire Templeman). 56 Eye to the Future: Research, Diagnostics, Therapeutics (Peter A. W. Rogers and Gareth C. Weston). 57 Fertility Preservation in Patients with Endometrioma (Jennifer Hirshfeld–Cytron, Candace Tingen, and Teresa K. Woodruff). Index.