The Placenta

Written by internationally recognized experts in the field, The Placenta: From Development to Disease is a clinical guide to identifying and managing problems in pregnancy associated with the placenta. Not only does this useful text detail the normal development of the placenta and fetus, a major component of the book focuses on abnormal placenta development and the resulting threats to the fetus and mother. Enhanced information is available throughout in helpful feature boxes highlighting “Clinical Pearls” and “Research Spotlights.” The Placenta: From Development to Disease is the only clinical guide to this key organ. Helen Kay, MD (Editor), D. Michael Nelson, MD (Editor), Yuping Wang, MD (Editor) CONTENTS List of Contributors. Foreword. Preface. Part 1: Fetal origins of adult disease/programming. 1 Maternal Undernutrition and Fetal Programming: Role of the Placenta ( Louiza Belkacemi, D. Michael Nelson, Mina Desai and Michael G. Ross ). 2 Cardiovascular Health and Maternal Placental Syndromes ( Shahzya S Huda and Ian A. Greer ). Part 2: Placental development, physiology and immunology. 3 Development and Anatomy of the Human Placenta ( Roxane Rampersad, Mila Cervar-Zivkovic and D. Michael Nelson ). 4 Immunologic Aspects of Pregnancy ( Joan S. Hunt and Margaret G. Petroff ). 5 Vascular Development in the Placenta ( Berthold Huppertz ). 6 Hypoxia and the Placenta ( Stacy Zamudio ). 7 Placental Metabolism ( Nicholas P. Illsley ). 8 Placental Hormones: Physiology, Disease and Prenatal Diagnosis ( Jennifer M. McNamara and Helen H. Kay ). 9 Placental Transfer in Health and Disease ( Caroline Wright and Colin P. Sibley ). 10 Placental Fat Trafficking ( Christina Scifres and Yoel Sadovsky ). 11 Maternal-Fetal Cell Trafficking and Microchimerism ( Hilary S. Gammill, Suzanne E. Peterson and J. Lee Nelson ). 12 Imprinting in the Human Placenta ( Shu Wen and Ignatia B. Van den Veyver ). 13 Placental membranes and amniotic fluid retention ( Marie H. Beall and Michael G. Ross ). Part 3: Examination of the placenta, membranes, cord. 14 Examination of the Placenta, Membranes and Cord ( Frederick T. Kraus ). 15 The Umbilical Cord ( Raymond W. Redline ). 16 Ultrasound Imaging and Doppler Studies of the Placenta ( Methodius G. Tuuli and Anthony O. Odibo ). 17 Magnetic Resonance Imaging and Positron Emission Tomography of the Placenta ( Christine H. Comstock and Helen H. Kay ). 18 Chorionic Villous Sampling and Amniocentesis ( Marion S. Verp ). 19 Cordocentesis and Fetoscopy ( Cristiano Jodicke and Ray Bahado-Singh ). Part 4: Research techniques to study the placenta. 20 Trophoblast Isolation and Culture ( Mila Cervar-Zivkovic and Christina Stern ). 21 Isolation and Culture of Human Umbilical Cord Vein Endothelial Cells ( Yuping Wang ). 22 Perfusion Technique for Studying the Placenta Cotyledon ( Leslie Myatt ). 23 Three-Dimensional Culture Modeling of the Placenta ( Douglas A. Kniss and Teng Ma ). 24 The Use of Ultrasound Contrast Agents in Placental Imaging ( Jacques S. Abramowicz ). 25 Microscopy and the Placenta ( William E. Ackerman IV, Toshihiro Takizawa and John M. Robinson ). 26 Proteomics & the Placenta ( Gregory E. Rice ). 27 Stable Isotope Methodologies for the Study of Transport and Metabolism In Vivo ( Irene Cetin and Chiara Mandò ). Part 5: Medical diseases and complications. 28 The Role of the Placenta in Autoimmune Disease and Early Pregnancy Loss ( Daniel L Jackson and Danny J. Schust ). 29 The Placenta in Preterm Prelabor Rupture of Membranes and Preterm Labor ( Chong Jai Kim, Roberto Romero and Sonia S. Hassan ). 30 Diabetes and the Placenta ( Ursula Hiden, Julia Froehlich and Gernot Desoye ). 31 Placental Origins of Intrauterine Growth Restriction ( Ian P. Crocker ). 32 The Placenta in Preeclampsia ( Fiona Lyall ). 33 Thrombophilia and the Placenta ( Christina S. Han and Michael J. Paidas ). 34 Infections in the Placenta ( Samuel Parry ). 35 Aneuploidy and Polyploidy ( Dan Diego-Alvarez and Wendy P. Robinson ). 36 Gestational Trophoblastic Disease and Placental Tumors ( Katja Gwin and Aliya N. Husain ). 37 Multiple Gestation and Twin-Twin Transfusion syndrome ( Ramesha Papanna and Kenneth Moise ). 38 Previa and Abruption ( Helen H. Kay ). 39 The Placenta as a Functional Barrier to Fetal Drug Exposure ( Tatiana N. Nanovskaya, Gary D. V. Hankins and Mahmoud S. Ahmed ). 40 Placental Drug Transport ( Clifford W. Mason and Carl P. Weiner ). Part 6: Future clinical applications. 41 Umbilical Cord Blood Banking ( Gilad A. Gross, Thinh Nguyen and Laura Meints ). 42 Stem Cells from the Placenta ( Thaddeus G. Golos ). 43 Fetal DNA, RNA and prenatal diagnosis ( Olav Lapaire and Wolfgang Holzgreve ).