Molecular Biology

Newly revised and updated, the Fourth Edition of Molecular Biology: Genes to Proteins is a comprehensive guide through the basic molecular processes and genetic phenomena of both prokaryotic and eukaryotic cells. Written for the undergraduate and first year graduate students within molecular biology or molecular genetics, the text has been updated with the latest data in the field. It incorporates a biochemical approach as well as a discovery approach that provides historical and experimental information within the context of the narrative. Reorganized to allow instructors to build on critical concepts throughout the course. Updated content on replication, transcription, and translation. A new chapter describing small silencing RNAs. New section added to examine RNA structure in greater detail. Includes a new section describing the ubiquitin proteasome proteolytic pathway. The section on DNA sequence has been updated to include the new generation of DNA sequencers. New sections have been added that examine epigenetic programming, which includes a discussion of imprinting and induced pluripotent stem (iPS) cells. Some Key Features Include: - Reorganized to allow instructors to build on critical concepts throughout the course. - Updated content on replication, transcription, and translation. - A new chapter describing small silencing RNAs. - New section added to examine RNA structure in greater detail. - Includes a new section describing the ubiquitin proteasome proteolytic pathway. - The section on DNA sequence has been updated to include the new generation of DNA sequencers. - New sections have been added that examine epigenetic programming, which includes a discussion of imprinting and induced  pluripotent stem (iPS) cells. * Teacher Supplements Available TABLE OF CONTENTS Section I Introduction Chapter 1 1. Introduction to Molecular Biology Section II Protein Structure and Function Chapter 2 Protein Structure Chapter 3 Protein Function Section III Nucleic Acids and Nucleoproteins Chapter 4 Nucleic Acid Structure Chapter 5 Techniques in Molecular Biology Chapter 6 Chromosome Structure Section IV Genetics and Virology Chapter 7 Genetic Analysis in Molecular Biology Chapter 8 Viruses in Molecular Biology Section V DNA Metabolism Chapter 9 DNA Replication in Bacteria Chapter 10 DNA Replication in Eukaryotes and the Archaea Chapter 11 DNA Damage Chapter 12 DNA Repair Chapter 13 Recombination Chapter 14 Transposons and Other Mobile Elements Section VI RNA Metabolism Chapter 16 Regulation of Bacterial Gene Transcription Chapter 17 RNA Polymerase II: Basal Transcription Chapter 18 RNA Polymerase II: Regulation Chapter 19 RNA Polymerase II: Cotranscriptional and Posttranscriptional Processes Chapter 20 RNA Polymerases I and III and Organellar RNA Polymerases Section VII Protein Synthesis Chapter 21 Small Silencing RNAs Chapter 22 Protein Synthesis: The Genetic Code Chapter 23 Protein Synthesis: The Ribosome