This pre-eminent work has developed over six editions in response to man's attempts to climb higher and higher unaided, and to spend more time at altitude for both work and recreation. Building on this established reputation, the new and highly experienced authors provide a fully revised and updated text that will help doctors continue to improve the health and safety of all people who visit, live or work in the cold, thin air of high mountains.
The sixth edition remains invaluable for any doctor accompanying an expedition or advising patients on a visit to altitude, those specialising in illness and accidents in high places, and for physicians and physiologists who study our dependence on oxygen and the adaptation of the body to altitude.
Table of Contents
Foreword
Acknowledgments
1. History of high altitude medicine and physiology
SECTION I. THE ENVIRONMENT AND ITS PEOPLE
2. The atmosphere
3. Geography
4. High altitude residents
5. Travelers and workers at high altitude
6. Genetics and genomics of exposure to high altitude
SECTION II. PHYSIOLOGIC RESPONSES TO HYPOXIA
7. Acclimatization
8. Pulmonary gas exchange
9. Control of breathing
10. Oxygen affinity and acid–base balance
11. Cardiovascular system
12. Central nervous system
13. Hematologic responses
14. Peripheral tissues
15. Energy balance and metabolism
16. Endocrine and metabolism
17. Sleep
18. Exercise
19. Physiology of extreme altitude
SECTION III. CLINICAL HIGH ALTITUDE MEDICINE
20. Acute mountain sickness
21. High altitude cerebral edema
22. High altitude pulmonary edema
23. Other medical conditions that occur at high altitude
24. Chronic altitude illness
25. High altitude travel with preexisting medical conditions
26. Children, the elderly, and women at high altitude
27. Other environmental illnesses in the mountains
Index
Andrew Luks is a Professor at the Division of Pulmonary, Critical Care & Sleep Medicine, Harborview Medical Center, The University of Washington, Seattle, USA
Phillip Ainslie is a Professor at the School of Health & Exercise Sciences and Co-Director, Centre for Heart, Lung & Vascular Health, The University of British Columbia, Okanagan, Canada
Justin Lawley is a Professor at the Institute for Sports Science, University of Innsbruck, Innsbruck, Austria
Robert Roach is an Associate Professor, Altitude Research Center, Division of Pulmonary Sciences & Critical Care, Anschutz Medical Campus, University of Colorado, Denver, USA
Tatum Simonson is an Assistant Professor, Division of Pulmonary, Critical Care & Sleep Medicine and Co-Director, Center for Physiological Genomics of Low Oxygen, University of California, San Diego School of Medicine, USA
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