Approximately five million children have been born worldwide as a result of assisted reproductive technology (ART). These techniques are now practised independently in most of the world's nations. Although the vast majority of ART parents and children are healthy following the procedures involved, there is an imperative to maintain a high standard of practice and monitor outcomes carefully. Interpretation of outcome data is difficult for a variety of reasons. As ART technologies evolve and new variants are established, the need for robust assessment of outcomes increases. This book gives a thorough review of potential complications of ART, with detailed analysis of outcome data for the various conditions described. A worldwide perspective is given throughout, with an international team of chapter authors.
Examines the clinical and laboratory complications and impacts of assisted reproductive technology (ART) at all stages, from patient preparation to birth
Discusses outcomes from the pregnancies of ART and possible mechanisms for development of malformations
Identifies surgical and medical interventions that could potentially be hazardous
Table of Contents
1. Ovarian cancer following use of clomiphene and gondadotropin in assisted reproduction Amin Philip Makar
2. Congenital anomalies following assisted reproductive technology Barbara Bosch and Alastair G. Sutcliffe
3. Extra-uterine pregnancy after artificial reproductive technology Jan Gerris and Steven Weyers
4. Minimizing multiple pregnancy after assisted reproductive technology Jan Gerris
5. Prevention of multiple pregnancy after IUI and ovarian stimulation Frank Vandekerckhove
6. Obstetric complications of twin pregnancy following assisted reproductive technology David Jackson, Brian Brocato and David F. Lewis
7. Selection of a single embryo for transfer Jana Liebenthron and Markus Montag
8. Complications of oocyte retrieval in assisted reproduction Elie Moubarak and Johnny Awwad
9. Ultrasound monitoring in ART: have we made any progress? Frank Vandekerckhove and Jan Gerris
10. Complications of polycystic ovary syndrome in assisted reproduction technology Ioannis E. Messinis, Christina I. Messini, George Anifandis and Konstantinos Dafopoulos
11. Ovarian hyperstimulation syndrome Botros Rizk
12. Genetics of ovarian hyperstimulation syndrome Botros Rizk, Rola Fawzi Q. Turki and Adel Abuzenadah
13. Prediction and prevention of ovarian hyperstimulation syndrome Annick Delvigne
14. Treatment of ovarian hyperstimulation syndrome Botros Rizk, Candice P. Holliday, Shaima Elbakhit Albasha and Daniel Antonious
15. Elimination of OHSS by GnRH agonist and freezing embryos Basil Tarlatzis, Julia K. Bosdou and Stratis Kolibianakis
16. Ethical and legal issues arising from complications of ART Gamal I. Serour and Bernard M. Dickens
17. Complications of gestational surrogacy Peter R. Brinsden
18. Complications of male fertility surgery for sperm retrieval in the azoospermic male Amr Abdel Raheem and David Ralph
19. Impediments, challenges and hurdles for lesbian, gay, bisexual and transgender persons seeking reproductive medicine Petra De Sutter
20. Political emotions and reproductive medicine: from individual suffering to European regulation
Index.
Botros Rizk is Professor and Head of Reproductive Endocrinology and Infertility and Medical and Scientific Director of USA In Vitro Fertilization and Assisted Reproduction at the University of South Alabama; Distinguished Adjunct Professor of Reproductive Endocrinology and Infertility Obstetrics and Gynecology at King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia; Distinguished Adjunct Scientific Director of IVF Michigan Rochester Hills; and President Elect of the Middle East Fertility Society.
Jan Gerris is Professor of Gynecology at Universiteit Gent, Belgium and has been Chairman of the Flemish Society of Obstetricians and Gynecologists since 2013. He is the founder and coordinator of the Special Interest Group for Safety and Quality in Assisted Reproductive Medicine of the European Society of Human Reproduction and Endocrinology.
Contributors
Amin Philip Makar, Barbara Bosch, Alastair G. Sutcliffe, Jan Gerris, Steven Weyers, Frank Vandekerckhove, David Jackson, Brian Brocato, David F. Lewis, Jana Liebenthron, Markus Montag, Elie Moubarak, Johnny Awwad, Ioannis E. Messinis, Christina I. Messini, George Anifandis, Konstantinos Dafopoulos, Botros Rizk, Rola Fawzi Q. Turki, Adel Abuzenadah, Annick Delvigne, Candice P. Holliday, Shaima Elbakhit Albasha, Daniel Antonious, Basil C. Tarlatzis, Julia K. Bosdou, Stratis Kolibianakis, Gamal I. Serour, Bernard M. Dickens, Peter R. Brinsden, Amr Abdel Raheem, David Ralph, Petra De Sutter
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