Now in its sixth edition, the Handbook of Drugs in Intensive Care is the essential guide to using drugs safely and effectively in the intensive care setting. The book is split into two sections: an A-Z guide to the drugs available, and concise notes on the key topics and situations faced on a daily basis. The A-Z section provides succinct information on each drug including uses, limitations, administration directions and adverse effects. The second section details practice guidelines such as insulin therapy, Parkinson's disease therapy when nil-by-mouth and drug dosing in renal failure. This revised edition includes seventeen new drug monographs and covers several new topics, including blood glucose management. A colour chart showing drug compatibility for intravenous administration included at the back of the book. Presented in a concise, compact format, this book is an invaluable resource for doctors, nurses, pharmacists and other healthcare professionals caring for critically ill patients.
Provides the latest information on drug therapy in the intensive care unit
New monographs have been added and old ones thoroughly updated
Includes a unique 'IV drugs compatibility chart' so that readers can identify compatible and non-compatible drugs combinations
Table of Contents
Introduction
How to use this book
Abbreviations
Acknowledgements
Drugs: An A-Z Guide
Prescribing using generic or brand names
Routes of administration
Loading dose
Drug metabolism
Enzyme systems
Drug excretion
Drug tolerance
Drug interactions
Therapeutic drug monitoring
Target range of concentration
Pharmacology in the critically ill
Body weight
Guide to ideal tidal volume
Cardiopulmonary resuscitation
Drugs in advanced life support
Management of acute major anaphylaxis
Management of acute severe hyperkalaemia
Management of malignant hyperthermia
Sedation, analgesia and neuromuscular blockade
Opioid conversion table
Antiretroviral drugs: alternatives for swallowing difficulties
Management of status epilepticus
Prevention of delirium tremens and alcohol withdrawal syndrome
Prevention of Wernicke–Korsakoff syndrome
Anti-arrhythmic drugs
Inotropes and vasopressors
Bronchospasm
Anti-ulcer drugs
Immunonutrition in the ICU
Corticosteroids
Short synacthen test
Bone marrow rescue following nitrous oxide
Heparin induced thrombocytopaenia
NOAC/DOAC
Antioxidants
Guidelines for patients with absent or dysfunctional spleen
Anti-microbial drugs
Bacterial gram staining
Antibiotics: sensitivities
Alterations to drug dosing in renal dysfunction and Haemo(dia)filtration
Chemical pleurodesis of malignant pleural effusion
Appendix A: creatinine clearance
Appendix B: weight conversion (stones/lb to kg)
Appendix C: body mass index (BMI) calculator
Appendix D: lean body weight charts
Appendix E: ideal tidal volume
Appendix F: estimated height from ulna length
Appendix G: infusion rate/dose calculation
Appendix H: drug compatibility chart
Appendix I: sodium content of oral medications
Appendix J: Drug management of the brain-stem-dead donor
Appendix K: vancomycin by continuous infusion
Appendix L: Child-Pugh score
Appendix M: severe sepsis algorithm
Appendix N: insulin guidelines
Drug index
