Bovine Tuberculosis

This book is contemporary, topical and global in its approach, and provides an essential, comprehensive treatise on bovine tuberculosis and the bacterium that causes it, Mycobacterium bovis. Bovine tuberculosis remains a major cause of economic loss in cattle industries worldwide, exacerbated in some countries by the presence of a substantial wildlife reservoir. It is a major zoonosis, causing human infection through consumption of unpasteurised milk or by close contact with infected animals.

Following a systematic approach, expert international authors cover epidemiology and the global situation; microbial virulence and pathogenesis; host responses to the pathogen; and diagnosis and control of the disease.

Aimed at researchers and practising veterinarians, this book is essential for those needing comprehensive information on the pathogen and disease, and offers a summary of key information learned from human tuberculosis research. It will be useful to those studying the infection and for those responsible for controlling the disease.

Table of Contents

    1: Bovine tuberculosis: worldwide picture
    2: Mycobacterium bovis as the causal agent of human tuberculosis: Public Health Implications
    3: Economics of bovine tuberculosis: a One Health issue
    4: The Epidemiology of Mycobacterium bovis Infection in Cattle
    5: Mycobacterium bovis molecular typing and surveillance
    6: Bovine Tuberculosis in Other Domestic Species
    7: Role of wildlife in the epidemiology of Mycobacterium bovis
    8: Molecular virulence mechanisms of Mycobacterium bovis
    9: The pathology and pathogenesis of Mycobacterium bovis infection
    10: Innate immune response in bovine tuberculosis
    11: Adaptive immunity
    12: Immunological Diagnosis
    13: Biomarkers in the Diagnosis of Mycobacterium tuberculosis Complex Infections
    14: Vaccination of domestic and wild animals against tuberculosis
    15: Managing Bovine Tuberculosis; Successes and Issues
    16: Perspectives on global bovine TB control